The Amazing Benefits of Berberine


One nutrient you could take could drastically improve diabetes and protect your peripheral nerves. Some studies even show it treats neurodegenerative diseases like Alzheimer’s, Multiple Sclerosis, Parkinson’s, Huntington’s disease, and cerebellar ataxia and help weight loss.

Berberine has taken the health industry by storm. Over 700 clinical studies are published annually on berberine, and scientists have been excited over the incredible findings.  

Can Berberine Benefit Diabetics?

Statistics show that more than 60 percent of people who have diabetes will develop peripheral neuropathy. Globally, 537 million adults, ages 20-79 years old, have been diagnosed with diabetes. Some predict the number will rise to 643 million people by 2030. 40% of the global population is walking around with undiagnosed diabetes.

How Does Diabetes Affect Me?

Furthermore, current research reveals that pre-diabetes can cause peripheral neuropathy. Pre-diabetes is a serious health condition where your blood sugar levels are higher than 100 mg/dL but lower than diagnosed diabetic levels at 126 mg/dL. 

Pre-diabetes raises your risk for peripheral nerve damage, neuron damage of the brain, heart disease, and stroke. 298 million adults globally are diagnosed with pre-diabetes. Both diabetes and pre-diabetes play an enormous role in developing peripheral neuropathy cases, but it goes even deeper.

Scientists link pre-diabetes, diabetes, and insulin resistance with the rising number of Alzheimer’s cases. Researchers are labeling it as Type 3 diabetes, and this is because neurons of the brain become unable to respond to insulin, which causes a cognitive decline we see in Alzheimer’s.

How Can Berberine Help Diabetes?

Over the last decade, numerous studies have shown that berberine benefits diabetics by effectively lowering blood glucose levels and improving insulin resistance. Research has shown that Berberine is EQUALLY as effective as metformin for improving insulin sensitivity.  

Insulin Resistance Chart
Insulin resistance pathological health condition in educational outline diagram

Using berberine and following a ketogenic diet is remarkably effective at drastically lowering blood glucose levels. Furthermore, berberine can treat diabetes by improving hemoglobin A1c as it restores insulin sensitivity.  

Reducing insulin resistance is critical because it’s linked to many severe diseases like fatty liver, high blood pressure, kidney disease, autoimmune diseases, and so many more.

In the regulation of lipid metabolism, berberine activity beats metformin. Other research studies have reported that berberine effectively lowers LDL cholesterol and triglycerides while raising HDL. These good cholesterols protect your heart and blood vessels. 

Berberine plays a significant role in protecting the inside wall of your blood vessels, called the endothelial layer. It can suppress oxidative damage to the endothelium of the blood vessel. Because of this, it can help dissolve plaquing inside of the blood vessels.  

Can Berberine Benefit Peripheral Neuropathy?

Berberine is neuroprotective, protecting nerve cells against chemical toxicity and assault. Recent studies show berberine inhibiting the production of neuroinflammation and oxidative stress. Berberine reduces nerve damage by protecting the nerves from this direct assault.

With significant advances in pharmacological research, berberine has gained widespread attention from scientists due to its role in helping neurodegenerative diseases in both the central and peripheral nervous systems.  

Numerous Clinical studies have found promising results for treating and managing symptoms for people suffering from Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, Multiple sclerosis, Cerebellar ataxia, and other central nervous system disease. 

Furthermore, berberine can reverse mitochondrial damage in peripheral nerves, the brain, and the spinal cord. Higher mitochondrial function improves oxygenation to the cells, improving ATP production or cellular energy. As a result, it assists in increasing the number of mitochondria in cells, especially nerve cells. 

Does Berberine Help You Lose Weight?

Berberine is being called Nature’s Ozempic. Ozempic is a drug that the FDA approved in Dec of 2017 for the treatment of Type 2 diabetes. However, it soared in the market by storm due to its ability to cause weight loss.  

Although these drugs successfully reduce weight, they come at a very high cost. Within a few years of its release, the side effects of Ozempic and similar drugs include possible thyroid tumors, including cancer. 

But more side effects correlate with Ozempic use, such as:

  • Pancreatitis
  • Gastroparesis (paralysis of the stomach muscles preventing food from being emptied)
  • Gallbladder disease
  • Intestinal blockage. 
  • Cases of severe or excessive vomiting.

These side effects aren’t just associated with Ozempic but also with other drugs in this class, such as Wegovy and Mounjaro.

Ozempic pen and measuring tape
Ozempic Insulin injection pen or insulin cartridge pen for diabetics

Because Ozempic is being grossly used for weight loss and not just diabetes, many insurance companies are refusing to cover this drug, and a one-month supply can cost between $500 and $900. There’s a much safer and cheaper alternative, and that’s BERBERINE.  

Although berberine doesn’t work the same way as Ozempic, research reveals it is very effective at weight loss, with no dangerous side effects.

A meta-analysis of 12 studies on berberine’s effect on weight loss shows that berberine significantly decreases body weight, body mass index, waist circumference, and C-reactive protein.  

C-reactive protein is the measurement of systemic inflammation. Berberine assists with weight loss and reduces inflammation. 

Furthermore, a one-month supply of berberine ranges between $50 to $60 a month with no horrific side effects. The only side effects reported with taking 1500 mg or more of berberine for long-standing periods have been nausea and loose stools. However, research has stated that these occurrences are extremely rare.

Other Benefits of Berberine

Beyond the many berberine benefits already mentioned, research shows that this nutrient is antimicrobial, antiviral, and antibacterial and can improve immune system function by improving T-cell function. T-cells are known as killer immune system cells because they go after foreign invaders and destroy them.

If you have a history of cardiovascular disease or heart attacks, berberine can treat and lower high blood pressure and prevent cardiac muscle fibrosis or scarring after a heart attack. It can also prevent scarring of the heart muscle brought on by a condition known as ischemia, where less oxygen reaches the heart muscle due to blockages.  

Berberine is also anti-thrombotic, which prevents blood clotting or thick, sticky blood, which is why doctors prescribe anticoagulants and antiplatelet medications.

Struggling with Neuropathy?

Book a consultation with one of America’s leading experts in peripheral neuropathy. Dr. Coppola and Dr. Monteiro have worked with neuropathy patients for almost 20 years and conduct seminars to help patients and doctors improve and reverse neuropathy.

To schedule an appointment, visit or call our customer service representatives at (844)400-0101. They are available Mondays through Fridays from 9 am to 5 pm EST.

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